Macular Degeneration

“Animals received syngeneic MSCs (1×106 cells) by tail vein at an age before major photoreceptor loss… both rod and cone photoreceptors were preserved (5–6 cells thick) at the time when control animal has a single layer of photoreceptors remained; Visual function was significantly preserved compared with controls… The number of pathological vascular complexes (abnormal vessels associated with migrating pigment epithelium cells) and area of vascular leakage that would ordinarily develop were dramatically reduced… There was an increase in neurotrophic factors within eyes of animals that received MSCs.”